According to a recent report, a high percentage of pregnant
women continue to take medication during their pregnancy despite the lack of
evidence regarding their safe use. The ethical problem with studying the
effects of medications on pregnant women and their babies has left a giant gap
in the safety data for common prescriptions.
The report, which appeared in the Journal of Obstetrics and
Gynecology, found that 70-80% of women have taken at least one medication
during the first trimester of their pregnancy and 50% of women are taking
prescription medication. These results are troubling because the possibility of
developing birth defects is highest during the first trimester. The study did
not specify which medications the women were taking.
The research raises many common questions, such as which medications are safe to take during
the first trimester? In which cases is it better to accept the risks of the
medication than to try to forgo it?
As women continue to take medications through their
pregnancies, new data is emerging. Recent revelations include:
- Topamax, a popular epilepsy drug that is often
used for migraines, can cause oral clefts.
- Topical steroids/corticosteroids increase the
risk of fetal growth retardation.
- Opioid painkillers such as codeine and oxycodone
were recently linked to a variety of birth defects including spina bifida.
(You can use the “Medication” tag listed on the right side
of the blog to keep up with any new information regarding medications during
pregnancy.)
Avoiding over-the-counter medications during the first
trimester is the best way to ensure that your baby develops safely. Consult
your doctor and pharmacist about taking any prescription medications throughout
your pregnancy. In some cases, such as severe depression or high blood pressure,
the benefits of taking medication could outweigh the risks. However, in many
situations there are natural ways to manage common ailments. Learn more about natural
remedies for common ailments
here.
Some over-the-counter
medications have been deemed safe to take after the tenth week of pregnancy. However, even mild pain killers, such as
acetaminophen and ibuprofen, that were previously deemed safe have recently been
under fire for possibly causing reproductive defects. Since almost half the
population of the US is on some type of medication, the situation remains very
confusing for many pregnant women. If you find you are pregnant and on
medication, talk to your doctor first and foremost. You also might want to do
an internet search for any recent information regarding the safety of the drug
during pregnancy. Use the drug index at the
FDA
website to locate a particular drug. The “Medication Guide” listed for the
drug will provide an updated list of counter-indications, including pregnancy.
Are you taking any
medications during your pregnancy?
Researchers report widespread use of medications among
pregnant women [
Eurekalert]
FDA: migraine drug ups risk for oral birth defects [
Reuters]
CDC: Some Painkillers Linked to Heightened Risk of Birth
Defects [
Fox
News]
Prescription Drug Use Continues to Increase: U.S.
Prescription Drug Data for 2007-2008 [
CDC]
Aspirin, acetaminophen and ibuprofen during pregnancy can
cause reproductive problems in male offspring [
LATimes]